Journal: Endocrine-Related Cancer

Article Title: Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

doi: 10.1530/ERC-18-0136

Figure Lengend Snippet: Strain-specific characteristics of MPC LUC/GZ allograft mice.

Article Snippet: For generation of metastases models, a single bolus of 100 µL cell suspension was injected intravenously into the tail vein of NMRI-nude mice ( n = 10), natural killer (NK) cell-depleted NMRI-nude mice ( n = 5), SHO mice (Crl:SHO- Prkdc scid Hr Hr , T and B cell-deficient, hairless; Charles River Laboratories; n = 9), SCID/beige mice (CB17.Cg- Prkdc scid Lyst bg-J /Crl, T and B cell-deficient, NK cell-defective, white-haired; Charles River; n = 9) and SKH1 mice (Crl:SKH1-Elite- Hr hr , immunocompetent, hairless; Charles River; n = 15).

Techniques: Injection, In Vivo, Histopathology, Imaging, Immunohistochemistry, Ex Vivo

Journal: Endocrine-Related Cancer

Article Title: Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

doi: 10.1530/ERC-18-0136

Figure Lengend Snippet: Renal monoamine excretion of subcutaneous and metastasized MPC LUC/GZ allograft models; (A) pathophysiologic changes in monoamine excretion profiles related to subcutaneous tumors in NMRI-nude mice, disseminated metastases in SCID/beige mice and liver metastases in SKH1 mice; (white data points, dashed line) physiologic excretion profile before tumor cell injection; (black data points, continuous line) excretion profile after a defined time of tumor growth; double-lined circles mark increasing urinary concentrations of epinephrine and metanephrine detectable in SCID/beige mice; (B and C) correlation between luminescence intensity of stumors and urinary concentrations of free catecholamines and O -methylated catecholamine metabolites; logarithmic scaling of x - and y -axes; significance of differences or relationships: * P < 0.05, ‡ P < 0.001; (DA) dopamine, (EPI) epinephrine, (MN) metanephrine, (MTY) 3-methoxytyramine, (NE) norepinephrine, (NMN) normetanephrine, (iv) intravenous, (sc) subcutaneous.

Article Snippet: For generation of metastases models, a single bolus of 100 µL cell suspension was injected intravenously into the tail vein of NMRI-nude mice ( n = 10), natural killer (NK) cell-depleted NMRI-nude mice ( n = 5), SHO mice (Crl:SHO- Prkdc scid Hr Hr , T and B cell-deficient, hairless; Charles River Laboratories; n = 9), SCID/beige mice (CB17.Cg- Prkdc scid Lyst bg-J /Crl, T and B cell-deficient, NK cell-defective, white-haired; Charles River; n = 9) and SKH1 mice (Crl:SKH1-Elite- Hr hr , immunocompetent, hairless; Charles River; n = 15).

Techniques: Injection, Methylation

Journal: STAR Protocols

Article Title: Optimized protocol for the generation of an orthotopic colon cancer mouse model and metastasis

doi: 10.1016/j.xpro.2022.102022

Figure Lengend Snippet:

Article Snippet: NMRI mice 5 weeks old female , Janvier Labs Saint Genest – Saint Isle - France , N/A.

Techniques: Recombinant, Sterility, Electron Microscopy, Software, Microscopy, Cell Counting